Monkey Drug Trials Experiment

Title: Monkey Drug Trials Experiment Authors: Deneau, Yanagita & Seevers Year: it was done in 1969 Purpose: The purpose of the experiment was to look at the effects of self-administration on drugs, drug abuse, and drug dependence in humans, by testing it on monkeys. They wanted to observe whether a monkey would become addicted to drugs or not, and to understand better the effects of drugs. Method: First a method was developed, to teach the monkeys how to self- administer the drugs through intravenous catheters.Then the psychologist injected the monkeys for the first time the drugs. Because they were several monkeys each one received a different drug, some received cocaine, morphine, amphetamines, nalorphine,mixtures, chlorprmazine, mescaline, codeine, pentobarbital, ethanol, and caffeine. The researchers observed a behaviour right afterwards the administration, and after some days they started to provided the prepared drug solutions to the monkeys to see, if they were going to self a dminister or not, afterwards they were already taught how to do it. Results:The results show that in consequence of the drug administration the monkeys became dependent on the drugs. The animals were out of their mind, that some tried desperately to escape and they broke their arms. The monkeys that took cocaine suffered convulsions, some other monkeys ripped off their own fingers (possibly because of hallucinations). Another monkey taking amphetamines took all of the fur from his arm and belly, and in the case of cocaine and morphine mixed, the monkeys died after two weeks. The psychological dependence of the drug effects occurs when the monkey oluntarily starts the self-administration of the drug. The monkeys developed psychological dependence on morphine, codeine, cocaine, d-amphetamine, pentobarbital, ethanol, and caffeine. All of the drugs except caffeine produced psychotoxicity. Monkeys didn’t created a psychological dependence on nalorphine, morphine-nalorphine mixture s, chlorpromazine, mescaline or physiological saline These experiments also showed that the monkey’s biological traits were similar to the human ones, and conclude that the key factor on drug abuse is the psychological dependence.The researchers founded the reason why drug abuse takes place and how can a psychological treatment will help people give up the drug addiction. Discussion: The experiment was very controversial because it was very unethical and the monkeys suffered a lot of pain, and in some cases died of overdose. The Helsinki declaration was founded in 1964 and since here they have been updating principles of good practice in this kinds of experiments. They say, â€Å"Welfare of animals used for research must be respected†. Since here the ethical views for non-humans subjects started.Later on the APA gave instructions to determine whether an experiments on animals is acceptable or not. For example animal research should not harm the animal or distress it on any way. If the researchers don’t follow this code, they wont be allowed to keep on with the experiment. In the case of this experiment was already done, but that’s why still now a days is very controversial and shocking, and is listed in one of the 10 most unethical psychological experiments. Personal opinion: This experiment in my opinion was useful to psychology.But I don’t agree with the methods that were applied. The researchers taught some behaviours to the monkeys that unless humans never show them how to do they will never do it by themselves, like self-administrating drugs, it is not something that in their natural environment are going to learn, so they are alienating the monkey from its normal behaviours. In my own opinion I know, that monkeys have very similar biological traits in compare to humans, and in this case I did find it useful because thanks to it, late in that times esearchers found the main key on drug dependence which is the psychologic al dependence the desire to always get more of the drug and feel what it makes you feel over and over again. Nowadays if they realize this experiment, we will say it’s not something new to humanity, that drugs create certain effects on the human body and clearly creates psychological dependence, but back in those days the use of drugs was just starting and this knowledge was not so obvious and known by so many people.I do agree it was unethical, doing those sort of things to the monkeys and probably In some cases there can be many differences between animal behaviour and human behaviour, therefore results for one another cannot be generalised. I would never do it, but after the realization of it, you analyse a little and the results are very useful, to act and treat on time a drug addiction. Sources * Psue76, â€Å"Monkey drug trails 1969† * Springer link â€Å"Psychopharmacology† * Mind power news â€Å" 10 most unethical psychological experiments† * Psychology Hawks â€Å"Psychology gone bad: when animals pay the price for  science. †

Introduction to International Business Essay Example | Topics and Well Written Essays - 1250 words - 2

Introduction to International Business - Essay Example Dells’ competitive environment, target market in other countries and communication strategy are also detailed in this paper. Dell Inc: Business and Market Overview Dell Inc designs, develops, manufacturers and markets computers, computer accessories and software products for both the customers of US and other countries. Dell Inc has long been marketing its computer products primarily based on a very strong marketing strategy of ‘going direct’ to its customers. In 2008, Dell was able to be placed as second in the worldwide PC market just behind Hewlett-Packard company. Dell has been gaining considerable growth in its market share during 2008 and 2009, with an increase of 1.2% growth which was the highest growth in the market (Gartner, 2009). The market share and related statistics of the major market players in 2010 show that Dell grew by 11.5 percent which is relatively less as compared to HP’s growth rate of 19.8 percent and Acer’s growth rate of 13 .5 % (Magee, 2010). ... In accomplishing this target, Dell will be meeting the customer expectations of highest quality, leading technology, competitive prices, accountability, flexible customization and financial stability (Farfan, 2011). Product Strategy Dell has been prospering on innovation and product differentiation as well. in 2003, Dell has been offering Latitude laptops, that were designed and developed to help business, government and institutional customers fulfill their computer-needs, and Inspiron laptops that were developed for users seeking the latest technology and high performance in more stylish and affordable packages (Ignatiuk, 2009, p. 20). Later, Dell added a number of different computer lines, they are Vostro, Precision, Alienware etc, to facilitate customers use different computers for their varying requirements. Distribution Strategy Dell is very known for ‘direct marketing’ as it has directly been selling its computer and accessories to the customers. Customers choose their items and order through either mail, or phone calls and the company send items to customers through its own delivery services or third party delivering facilities. As Bozarth (2005, p. 22) stressed, Dell’s direct-marketing strategy has been primarily based on a build-to-order manufacturing system. It means that Dell manufacturers computers only when they have actual customer orders and demands and this has been a reason why Dell succeeded within few years despite rigorous competition in computer marketing. Thomas (2002, p. 163) stated that Michael Dell has long been pursuing ‘going direct’ to customers approach, being aligned with virtual integration strategy. The company was using web-technology to blur

Financial statements Essay Example | Topics and Well Written Essays - 500 words

Financial statements - Essay Example report that measures the success of the company operations for a particular period of time and this is used by business and investment people to determine the profitability, investment value and creditworthiness etc (Keiso and Weygandt, 2007, p. 126). Income Statement summarizes revenues, gains, expenses and losses. Sales, fees, dividends and interest are parts of revenues, while expenses take forms of cost of goods sold, depreciation, interest, wages and salary etc. Gains and losses are different types like sale of plant assets or investments, settlement of liabilities etc. Expenses are debited and revenue are credited, and the total of these can be a net debit (loss) or net credit (profit). Income statement evaluates the past performance of the company and provides a basis for future prediction and assessing risk or uncertainty. The Balance Sheet presents the financial position of the business through the main elements that are called assets, liabilities and stockholders’ equity (Davies and Pain, 2002, p. 49). Assets include those that can provide future economic benefits as a result of past transaction (plant, machinery, vehicles and all) and liabilities include those that are probable future sacrifices of economic benefits arising from present obligations- loan, overdraft etc- (Keiso and Weygandt, 2007, p. 173). Assets are regarded to be debit balances and liabilities and stockholder’s equity are credit balances. Balance sheet is always in a balance and hence it can be summarized as: Neither balance sheet nor income statement show or directly analyze some of the key changes taken place in the financial position. They don’t show cash inflows and cash outflows that are in turn, highly important to know and assess the timing and uncertainty of cash flows. Cash-flow statement, instead, provides cash inflows and outflows and it calculates the net changes in the cash position of the business. It comprises of 1) operation activities which are cash effects of

Saudi Aramco Procurement Process Essay Example | Topics and Well Written Essays - 3250 words

Saudi Aramco Procurement Process - Essay Example The millennium is characterized with information technology as instrument for world wide business expansion, networking and in engaging with business partners for sustainable operations. Information technology also improved communication processes and hastened responses to corporate needs and systematized all operations. For some institutions and companies, this optimized virtual mechanism for complex procedures by thoroughly mainstreaming transactional contract relations. This means that through technology, corporation evolved into certain level of structural sophistication in centralizing internal mechanism and resolving once complex manual procedures, including assertiveness in the interaction of business decision processes. All this are made possible through the development of systematized digitized system of information technology. This essay will attempt to explicate and illustrate how information technology improved procedural procurement engendered organizational readiness in terms of corporate financial and technological resources as well as of its capacity to respond to external pressure due to competition with trading. Transactional relations of contact and procurement are now even done using the internet. It will also attempt to analyze if hard system model befits Saudi Aramco Company’s procurement procedures. Procurement Procedure is a process on how a contract is obtained. It is a mechanism to control the nature, object, expectations, and delivery of outcome based on agreements. It is a universal mechanisms adopted by companies and institutions that are operating in large scale, or in a multi-enterprise level with expensive capital investments but is constantly confronted with concerns on production technologies adaptation, volatile markets and pervasive regulation (Estache & Atsushi (2008). This situation is true with oil and gas extractive industries where there are standards and control mechanism that should be adopted to systematize its operations. This is considered as complexity management. Managing Information System There is a systematic approach used in managing information systems. This approach is technology-focused, process-sensitive, quantitative and qualitative in application and methodical in analysis, procedures, tools and techniques (Dumitrascu, 2006). This is evident in computerized system designed by infotech experts like Cisco. It helped in knowledge management and in systematizing transactions by increasing it company’s corporate virtual realities, although these require persons equipped with knowledge to ensure that the system will be effectively interactive. This means that the person must be knowledgeable too in maximizing digitized information in documentation as well as in technical system optimization to protect it from overload and techie backlog. Complexity management treats all hard structured and soft unstructured problems. Its system is rational, scientific and logical and itâ₠¬â„¢s developed with the assumption that the world is clear out there and can be customized based on our needs (Dumitrascu, 2006). Complexity management can be done using varied diagrams. This can be Spray Diagram, Systems Maps, Influence Diagrams, Multiple-cause diagrams, Sign graphs, and Control Model Diagram. These are explicated as follows: a. Influence Diagram— also known as relevance  analysis or a decision network illustrated graphical and mathematical representation in decision-making. It was developed in 1970s and is now adopted widely and becoming an alternative to  decision tree which typically suffers from  exponential growth  in number of branches with each variable modeled (Detwarasiti and Shachter, 2005 ; Holtzman,1989). ID is practicable for team decision analysis because it allows incomplete sharing of information among team members to be modeled and solved explicitly. The semantic of

Graduating College Essay Example | Topics and Well Written Essays - 1000 words

Graduating College - Essay Example Additionally, it examines the message being conveyed and its effectiveness as used by the author. This paper makes a rhetorical analysis of a piece of work written by Rodney Smith, examining the effectiveness of the various styles used by the author and the intended message. The item, â€Å"Yes, A College Education is Worth the Costs† was written by Rodney Smith, who after being compelled by the situations in his upbringing, thought that having a college education was an important step and process for any person, since it opens that person to the many adventures and opportunities of life (Smith para 6). Rodney comes from a family that values education as an important and effective investment that gives many people opportunities in life. Rodney’s father was helped to pursue his education by his grandma, who thought that having this education would help him make his life in the most effective way. Initially, his grandfather was of the opinion that he undertakes faming, but the pressure from his grandmother ensured that he pursued his education, managing to get a law degree that made all the difference in his life and family. In this case, it becomes evident that the author of the text seems to have a firm understanding and awareness of the need for education and that his support is not founded on misconceptions. After analyzing this text, it is evident that Rodney, the author of this text had an implied purpose for writing this text. The goal of this writer in making this text is actually to convince those that do not see any value in education about its significance. This can be understood from the way, he gives detail to the path to his education. Explaining how his grandma had to convince his grandpa to invest in educating his dad. After graduating with a law degree, his father realized that by educating his children, they would also have a better life. Rodney understands that many people exist who do not see any

Business law Essay Example | Topics and Well Written Essays - 2500 words

Business law - Essay Example However, the Council may not be held liable for the losses of 50,000 pounds that Burton is trying to claim in the form of lost profits. The original neighbor principle mandating a general duty of care towards others on the basis of owing consideration to one’s neighbor, was set out in the case of Donaghue v Stevenson.1 This was later refined in the case of Caparo v Dickman2 where the scope of the duty of care was refined on the basis of three principles: (a) was there a relationship of sufficient proximity between the plaintiff and the defendant? (b) Was the damage caused to the plaintiff reasonably foreseeable? (c) Is it just and reasonable to impose a duty of care? This may be applied in the case of both Abi and Burton, who have suffered damages in the form of repairs needed for their homes, with Abi also sustaining injuries. Abi is a local resident of the area and Burton’s is a local business, therefore the Council is responsible for ensuring their safety by maintaining the flood barrier. Secondly, the damage caused is likely to be held to be reasonably foreseeable because Hanby Borough Council is responsible for maintaining flood defenses along the river and were told to improve the defenses. Since a flood had occurred before, it is reasonable to assume that such damages occurring in the future would have been a foreseeable event and therefore the Council may be held to be negligent in failing to complete repairs quickly. Lastly, the Court may indeed deem it just and reasonable to impose a duty of care in this case, since the negligence of the Council has resulted in damages caused to the premises of both Abi and Burton, as well as fu rther injuries to Abi while she was being rescued which required hospitalization. The underlying core for the establishment of the principles wherein negligence has been held to be legally liable under the principles spelt out in the cases above, is the sentiment of moral wrong doing for which the offender is to be held

Sales agreement Essay Example | Topics and Well Written Essays - 250 words

Sales agreement - Essay Example 15 important points are elaborated, in which it starts with the product limited warranty. Acer emphasizes that no defects in materials will disturbed and provided workmanship during the limited warranty period if reparation is needed due to certain options. Fortunately, buyers can have hardware technical support via on-line, telephone and other methods. Buyers should be careful to use their own software since it might have errors that have no relation to be assisted by Acer. For the on-site service, buyers should understand their locations, because there are regulations of distance and geographical areas from Acer. Point number 5 (five) of â€Å"Limitations and Exclusions† be carefully noticed; in this case, those are things that Acer is not responsible for such as damages caused by personal faulty, damages caused by combination made to the products with other non-Gateway branded products, and mice problem at buyer’s place. Next, buyers should be on time to make registr ation of their warranty within 30 days after the purchase. Assistance from buyers is needed when there are problems to repair, and Acer want them to keep the data on other devices when the reparation is about to be done.